We used the methods of valuation certificates ...

BACKGROUND / RATIONALE: The expected value of information (IEU) analysis allows researchers to estimate returns to research. We used the methods of lasix and heart failure valuation IEU national judicial treatment of emphysema (net) multicenter randomized trial of lung volume reduction surgery (LVRS) compared with drug therapy (MT) in patients with severe emphysema, then compared the outcome of court costs. Methods: We collected information on the costs and benefits of LVRS and MT to the court and the costs of the NETT, and compared these data with the results of cost-effectiveness analysis conducted alongside the court. We used 2 threshold for submission of the social relevance of quality adjusted life year (QALY): $ 50,000 and U.S. $ 100 000. The results of the economic efficiency of LVRS compared with historical MT (nontrial) Information USD 305,000 / QALY. Based on these data and additional threshold value return value expected value of perfect information was USD 46 million USD 670 million threshold $ 50,000 and 100,000 dollars per QALY, respectively. NETT was equipped with 1250 patients in each group, ultimately, about 600 patients in each group were employed. From 1250 patients in the hand, the expected value of sample information was $ 660 million threshold for 100,000 dollars. Actual costs of NETT is approximately $ 60 million. The expected net profit of the sample was $ 600 million. Conclusions: Given the difference between the trial and economic benefits of information IEU analysis shows that the federal investment in the NETT trial represented good value for money. .